Common symptoms
- Diarrhoea, loose or greasy stools
- Bloating, wind and abdominal discomfort after eating
- Tiredness and low energy
- Unexplained weight loss
- Iron deficiency anaemia or low B12, folate or vitamin D
- Mouth ulcers
- An itchy, blistering skin rash (dermatitis herpetiformis)
- Symptoms after dairy or particular foods
Conditions diagnosed and managed
- Coeliac disease
- Gluten-related digestive problems
- Lactose intolerance
- Food intolerances
- Nutritional deficiencies (iron, B12, folate, vitamin D)
- Malabsorption disorders
What is coeliac disease?
Coeliac disease is an autoimmune condition in which eating gluten — found in wheat, barley and rye — damages the lining of the small bowel. This reduces the body’s ability to absorb nutrients. It affects around 1 in 100 people in the UK, but many remain undiagnosed because symptoms can be mild or unusual.
Coeliac disease testing and diagnosis
Testing starts with a blood test for coeliac antibodies. In adults, the diagnosis is usually confirmed with a gastroscopy and small bowel biopsies.
Important: keep eating gluten until testing is complete. Cutting it out beforehand can make the blood test and biopsies falsely normal.
Gluten-related digestive problems
Some people get symptoms from wheat or gluten without having coeliac disease. This may be due to sensitivity to the fermentable carbohydrates in wheat, which overlaps with IBS, rather than gluten itself. Excluding coeliac disease properly first is essential, because the implications are very different.
Lactose intolerance and other food intolerances
Lactose intolerance occurs when the gut produces too little of the enzyme needed to digest milk sugar, causing bloating, wind and diarrhoea after dairy. It can be primary, or secondary to another condition such as coeliac disease or a recent infection. Other food intolerances are common, but commercially sold “intolerance tests” are generally unreliable — a structured, specialist-guided approach is far more useful. Food allergies that cause hives, swelling or breathing problems are a separate issue and need an allergy assessment.
Malabsorption and nutritional deficiencies
Malabsorption means the gut is not absorbing nutrients properly. Clues include unexplained weight loss, pale or greasy stools that are hard to flush, and deficiencies in iron, B12, folate or vitamin D. Causes include coeliac disease, pancreatic insufficiency, bile acid problems, small bowel bacterial overgrowth and Crohn’s disease.
How Dr Khalid investigates the problem
Dr Khalid will review your symptoms, diet and any previous results. Investigations may include:
- Coeliac antibody blood tests (while you are still eating gluten)
- Blood tests for iron, B12, folate, vitamin D and other nutrients
- A gastroscopy with small bowel biopsies
- Breath tests for lactose intolerance or bacterial overgrowth where available
- Stool tests to assess pancreatic function
Treatment and management
Coeliac disease is treated with a strict, lifelong gluten-free diet, ideally supported by a dietitian, with follow-up to check that the gut is healing and deficiencies are corrected. For intolerances, the aim is to identify true triggers and keep your diet as varied as possible. Where malabsorption is found, the underlying cause is treated and nutritional deficiencies are replaced.
When should you see a gastroenterologist?
See a specialist if you think food is triggering your symptoms, have a family history of coeliac disease, have unexplained anaemia or vitamin deficiencies, or have a positive coeliac blood test.
Book a private consultation at Spire Cheshire in Warrington or The Highfield Hospital in Rochdale.
When to seek urgent help
Don’t wait for a routine appointment. Call 999 or go to A&E if you have:
- Vomiting blood or material that looks like coffee grounds
- Black, tarry stools or heavy rectal bleeding
- Severe or worsening abdominal pain
- Food stuck and being unable to swallow
- Yellowing of the skin or eyes with fever or pain
Frequently asked questions
Should I stop eating gluten before I am tested?
No. Continue eating gluten in more than one meal a day for at least six weeks before testing, otherwise the blood test and biopsies may be falsely normal.
Are home food intolerance tests reliable?
Most commercially available food intolerance tests, including IgG blood tests and hair analysis, are not supported by good evidence. A structured assessment with a specialist and dietitian is more reliable.
Can coeliac disease develop in adulthood?
Yes. Coeliac disease can be diagnosed at any age, and many people are diagnosed in their 40s, 50s or later.
Medically reviewed by Dr Sal Khalid, Consultant Gastroenterologist. Last reviewed November 2026. This page is general information and does not replace a personal medical consultation.